Tranexamic Acid and Total Joint Arthroplasty

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Tranexamic Acid in Total Joint Arthroplasty: Efficacy and Safety

  Despite improvements in surgical and anesthetic techniques, total joint arthroplasty (TJA) is still associated with substantial blood loss and postoperative anemia (1). A considerable portion of patients with postoperative anemia require blood transfusion, which has been shown to negatively affect the outcome of TJA and predisposes patients to development of surgical site infection and peripr...

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Tranexamic acid in total joint arthroplasty.

Total Joint Arthroplasty (TJA) is one of the most common orthopaedic procedures performed worldwide that restores function and allows patients to maintain their activities of daily living [1] Optimizing patients for surgery is of utmost importance, including conserving blood to minimize the risk of surgical site infection since immunomodulatory effects of allogenic blood [2] predisposes TJA pat...

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tranexamic acid in total joint arthroplasty: efficacy and safety

despite improvements in surgical and anesthetic techniques, total joint arthroplasty (tja) is still associated with substantial blood loss and postoperative anemia (1). a considerable portion of patients with postoperative anemia require blood transfusion, which has been shown to negatively affect the outcome of tja and predisposes patients to development of surgical site infection and peripros...

متن کامل

Tranexamic Acid in total joint arthroplasty: efficacy and safety.

Despite improvements in surgical and anesthetic techniques, total joint arthroplasty (TJA) is still associated with substantial blood loss and postoperative anemia (1). A considerable portion of patients with postoperative anemia require blood transfusion, which has been shown to negatively affect the outcome of TJA and predisposes patients to development of surgical site infection and peripros...

متن کامل

Tranexamic acid plus diluted-epinephrine versus tranexamic acid alone for blood loss in total joint arthroplasty

BACKGROUND We conducted the present meta-analysis to assess the efficacy and safety of tranexamic acid (TXA) plus diluted-epinephrine (DEP) for patients with total joint arthroplasty (TJA, including total knee arthroplasty (TKA) and total hip arthroplasty (THA)). METHODS Electronic databases (PubMed, EMBASE, the Cochrane Central Register of Controlled Trials (CENTRAL), Chinese Wanfang databas...

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ژورنال

عنوان ژورنال: Journal of Blood & Lymph

سال: 2014

ISSN: 2165-7831

DOI: 10.4172/2165-7831.1000e114